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Whitesides has developed a
low-cost and portable microfluidic immuno-assay kit for use in the field.
The device uses amplification chemistry based on silver deposition on gold-conjugated
antibodies. It is compatible with microfluidic flow, and is easily detected
by a battery-operated detector or by eye. The device exhibits high sensitivity,
and can detect anti-HIV antibodies in a sample of human serum diluted 10,000-fold.
The device is robust and uses inexpensive components, making it suitable
for deployment in the third world where there is a strong need for this
sort of instrumentation. This work couples well to the effort lead by Edwards,
whose course in bioengineering has spawned a non-profit start-up, MEND,
or Medicine in Need, which is dedicated to the development of an inexpensive
cure for TB for the third world.
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